Anti-RIP Rabbit Polyclonal Antibody

Supplier: Genetex

GTX22563
89361-290EA 380.82 USD
89361-290
Anti-RIP Rabbit Polyclonal Antibody
Antibodies
RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase, which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis factor receptor (TNFR1). It is a cell death domain adapter protein, which can bind to the adapter proteins TRADD, RAID, and TRAF2. RIP contains an N-terminal region with homology to protein kinase, an intermediate domain capable of association with MAPKKK and a C-terminal region containing an intracellular death domain motif. RIP activates both p38 MAP kinase and SAPK families. In vitro, RIP induces apoptosis, as well as SAPK/JNK and NF kappa B activation. RIP possesses kinase activity as it autophosphorylates itself on serine and threonine residues.

WB: Use at a concentration of 1 - 2 ?g/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: RIP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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