IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion. But it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
Recommended Starting Dilutions:ELISA: Use at a concentration of 0.5 µg/mL. WB: Use at an assay dependent dilution. Predicted molecular weight: 51.4 kDa.Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Secondary
Antigen: IgE
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Rat