CD200 is the ligand for a receptor restricted to myeloid cells, which delivers inhibitory signals. In the CD200 deficient mouse model myeloid cells are more activated when stimulated immunologically than cells from normal mice. CD200 delivers the crucial intracellular signal leading to immunosuppression, important in autoimmunity and transplantation. Regulation of CD200 expression may control both pregnancy and allograft survival.
Recommended Starting Dilutions:Flow Cytometry: 1/50 - 1/100Not tested in other applications. Optimal dilution / concentration should be determined by the end user.
Type: Primary
Antigen: OX2R
Clonality: Monoclonal
Clone: OX108
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human