Anti-OPG Rabbit Polyclonal AntibodySupplier: GeneTex
89360-386EA 585.53 USD89360-386
Anti-OPG Rabbit Polyclonal Antibody
Osteoprotegerin (OPG) belongs to the TNF receptor (TNFR) family. Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
ELISA: Use at a concentration of 0.15 - 0.30 ?g/ml. WB: Use at a concentration of 0.1 - 0.2 ?g/ml. Predicted molecular weight: 48 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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