NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. The IkB kinase (IKK) phosphorylates IkB, and mediates IkB degradation and NFkB activation. IKK is a serine protein kinase. The beta subunit is part of the IKK complex.
IP: 2?g of antibody is recommended for performing immunoprecipitation. WB: Use at a concentration of 1-2 ?g/ml. Detects a band of approximately 87 kDa (predicted molecular weight: 90.7 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: IKBKB
Clonality: Monoclonal
Clone: 10A9B6
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human