Anti-HMW Kininogen Mouse Monoclonal Antibody [clone: 2B5]

Supplier: GeneTex
89360-944EA 623.28 USD
Anti-HMW Kininogen Mouse Monoclonal Antibody [clone: 2B5]
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Dilute in PBS or medium which is identical to that used in the assay system. This antibody can neutralize the inhibitory activity of HMWK on platelet calpain. This antibody can also be used for coagulation studies.

Type: Primary
Antigen: HMW Kininogen
Clonality: Monoclonal
Clone: 2B5
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
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