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Anti-TXNRD2 Rabbit Polyclonal Antibody

GTX15173

89350-978EA 376.73 USD

89350-978

Anti-TXNRD2 Rabbit Polyclonal Antibody

The reduced form of thioredoxin serves as a hydrogen donor, contributes to the up-regulation of various transcription factors and binds to and inhibits MAPKKK activity. Oxidized thioredoxin is converted back to the reduced form by Thioredoxin Reductase (TrxR2), a redox active enzyme. There are two distinct isoforms in mammalian cells, TrxR1, a cytosolic protein and TrxR2, almost exclusively a mitochondrial protein. TrxR expression is induced in several tumors.

IHC-P: Use at a dilution of 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. WB: Use at an assay dependent dilution. Predicted molecular weight: 56 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: TXNRD2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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