Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
IHC-P: 1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol with 10 mM citrate buffer, pH 6.0. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: CGA
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: