After binding Acetylcholine, the Nicotinic Acetylcholine Receptor (AChR) responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR seems to be composed of two different type of subunits: alpha and beta. This antibody binds to native subunits as well as denatured subunits although with lower affinity. Clone 270 is useful for immunoisolating and pharmacologically characterizing AChRs, immunopurification of AChRs, and is also useful histologically.
Type: Primary
Antigen: CHRNB2
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype:
Reactivity: