Anti-NF2 Rabbit Polyclonal Antibody

Supplier: GeneTex

89361-252EA 425.42 USD
Anti-NF2 Rabbit Polyclonal Antibody
The recently isolated neurofibromatosis 2 tumor suppressor gene encodes a 595 amino acid protein (Merlin). The protein product Merlin, named for its relatedness to the ezrin, radixin and moesin (ERM) family of proteins, is a tumor suppressor whose absence results in the occurrence of multiple tumors of the nervous system, particularly schwannomas and meningiomas. Merlin's similarity to ERMs suggests that it might share functions, acting as a link between cytoskeletal components and the cell membrane. The NF2 protein is highly expressed in human fibroblasts and detected as a single band of about 75kD. This antibody is specific for the phosphorylated form of human NF2 (Merlin).

ELISA: Only tested against immunizing peptide. Western blot: use at 1:1000 dilution - Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.

Type: Primary
Antigen: NF2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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