CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa).
FACS: Use at an assay dependant concentration. FuncS: Use at an assay dependant dilution. The antibody induces FcgR-dependent platelet activation (aggregation). IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use under non-reducing conditions. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: CD9
Clonality: Monoclonal
Clone: MEM-61
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: