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Anti-14-3-3 Mouse Monoclonal Antibody [clone: 3F7]

Supplier: Genetex
GTX14110
Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf-1 kinase activity and phosphorylation amoung many other functions.

IP: Use at an assay dependent dilution. WB: Use at a concentration of 1 - 2 mg/ml. Predicted molecular weight: 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: 14-3-3
Clonality: Monoclonal
Clone: 3F7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
50 μl GTX14110 89359-942 Each (50µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol 14-3-3
Antigen Name 14-3-3 protein
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone 3F7
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoPrecipitation Yes
Antigen Synonyms Alpha polypeptide, 14-3-3 alpha, protein kinase C inhibitor protein-1, Protein 1054, brain Protein 14-3-3, Protein kinase C inhibitor protein 1, beta isoform, 14-3-3 Protein beta/alpha, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
Gene ID 56011
Concentration 1 mg/ml
Immunogen Recombinant full length protein (Human 14-3-3 gamma).
Purification Protein G purified
Storage Buffer Preservative: NoneConstituents: PBS. pH 7.4
Storage Temperature Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Tested Applications IP, WB
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