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Optiferrin™ Recombinant Transferrin, InVitria

Supplier: Invitria

Optiferrin is recombinant human transferrin that is completely animal component free.

  • Animal-free
  • No cell damage
  • Cost-effective
  • Replaces bovine transferrin and plasma derived human transferrin
  • Replaces iron chelators and other iron sources
  • Well defined and consistent
Optiferrin's performance is equivalent to human transferrin in cell culture and offers significant regulatory advantages due to its safety and consistency. Optiferrin is produced in an animal-free system (ExpressTec), which eliminates safety concerns associated with animal or human derived transferrin that can cause contamination with viruses and prions. In addition, Optiferrin is a consistent product with none of the lot-to-lot variability seen in other transferrins and is an excellent animal-free replacement for bovine transferrin and plasma-derived human transferrin.

As a universal iron carrier, Optiferrin also provides better performance than other iron sources and iron chelators. All cells need iron for cell division and transferrin is specifically designed to deliver iron to the cells. Each cell has transferrin receptors that ensure optimal iron delivery based on the actual iron need of the cells. The cells decide how much iron they need, thus eliminating the problem of too much iron causing cell damage. The problem with alternative iron sources and iron chelators is that cells cannot regulate the amount of iron that is delivered and studies have shown that cells can take in 100 times physiological intracellular iron. The uptake of too much iron causes significant cell damage and other iron sources can cause oxidative damage which also causes cell damage; neither of these types of damage can occur when transferrin is used.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 g 777TRF029-1G 10847-770 Each (1g) Retrieving
10 g 777TRF029-10G 10847-778 Each (10g) Retrieving
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SPECIFICATIONS

Endotoxin Content ≤1 EU/mg
Formulation Powder, pH (1% solution) 6.0-8.0
Moisture <10%
Protease-free Yes
Protein Type Recombinant
Protein/Peptide Name Optiferrin Transferrin
Protein/Peptide Type Recombinant
Purity >95%
Solubility (1%, A600nm) <0.5
Species Human
Total Protein >90%
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