HALO® HPLC Columns for Biopharma Separations

Advancing the understanding of form and function for biomolecules, researchers supporting their development and release employ many orthogonal techniques and separation methodologies to develop a more complete therapeutic picture.

With both tailored particle and pore size options, HALO® BIOCLASS offers application-specific solutions for:

  • Intact proteins, monoclonal antibodies (mAbs), biosimilars, and other large biomolecules such as pegylated proteins, antibody-drug conjugates (ADCs), etc.
  • Peptide mapping (analysis of enzyme digests) for characterization and monitoring of synthetic protein drugs
  • Analysis of therapeutic peptides and peptide biomarkers (protein surrogates)
  • High-resolution separations of complex mixtures of glycans released from N- and O-linked glycoproteins

PROTEIN SEPARATIONS

PEPTIDE SEPARATIONS

GLYCAN SEPARATIONS